Biological Effective Dose (BED) Calculator
Biological Effective Dose (BED) Calculator
Biological Effective Dose (BED) Calculator
What is a Biological Effective Dose (BED) Calculator?
How can we calculate the biological impact of a radiation dose? The Biological Effective Dose (BED) Calculator is a tool that helps determine the effective dose of radiation therapy by considering the total dose, number of fractions, and alpha/beta ratio. Enter these values into the calculator to find the BED.
How to Use the BED Calculator
To use the BED Calculator is simple. Here’s a stepbystep guide:
 Total Dose (Gy): Enter the total radiation dose in Gray (Gy).
 Example: 60 Gy
 Fractionation Number: Enter the number of fractions.
 Example: 30
 Alpha/Beta Ratio: Enter the alpha/beta ratio in Gray (Gy).
 Example: 10 Gy
Once you enter these values, press the "Calculate" button to see the Biological Effective Dose.
What is Biological Effective Dose (BED)?
The Biological Effective Dose (BED) is a measure used in radiation therapy to quantify the biological effect of a given dose of radiation. It accounts for the total dose, the number of fractions, and the tissuespecific alpha/beta ratio.
Formula
The formula to calculate the Biological Effective Dose (BED) is:
 BED = Total Dose * (1 + (Fraction Dose / Alpha/Beta Ratio))
Variables
Variable  Description 

Total Dose  The overall radiation dose in Gray (Gy) 
Fractionation Number  The number of fractions the dose is divided into 
Alpha/Beta Ratio  The alpha/beta ratio specific to the tissue in Gray (Gy) 
Calculation Example
Example 1
 Total Dose: 60 Gy
 Fractionation Number: 30
 Alpha/Beta Ratio: 10 Gy
StepbyStep Calculation:
1. Calculate the fraction dose:

 Fraction Dose = Total Dose / Fractionation Number
 Fraction Dose = 60 / 30
 Fraction Dose = 2 Gy
2. Calculate the BED:

 BED = Total Dose * (1 + (Fraction Dose / Alpha/Beta Ratio))
 BED = 60 * (1 + (2 / 10))
 BED = 60 * (1 + 0.2)
 BED = 60 * 1.2
 BED = 72 Gy
3. Result:
 BED = 72 Gy
Example 2
 Total Dose: 50 Gy
 Fractionation Number: 25
 Alpha/Beta Ratio: 8 Gy
StepbyStep Calculation:
1. Calculate the fraction dose:

 Fraction Dose = Total Dose / Fractionation Number
 Fraction Dose = 50 / 25
 Fraction Dose = 2 Gy
2. Calculate the BED:

 BED = Total Dose * (1 + (Fraction Dose / Alpha/Beta Ratio))
 BED = 50 * (1 + (2 / 8))
 BED = 50 * (1 + 0.25)
 BED = 50 * 1.25
 BED = 62.5 Gy
3. Result:
 BED = 62.5 Gy