Hardy-Weinberg Equilibrium Calculator

How to determine if a population is in genetic equilibrium? The Hardy Weinberg Equilibrium Calculator helps you figure this out. Just enter values into the calculator, one can find out if the population follows the Hardy-Weinberg principle.

What is Hardy-Weinberg Equilibrium?

The Hardy-Weinberg Equilibrium is a principle in genetics. It states that allele and genotype frequencies in a population remain constant from generation to generation, given certain conditions. This equilibrium helps scientists understand genetic variation in populations.

Hardy-Weinberg Equilibrium Calculator







Results

Chi-squared:

Expected Common Homozygotes:

Expected Heterozygotes:

Expected Rare Homozygotes:

hwe calculator

How to Use the Calculator

To use the Hardy-Weinberg Equilibrium Calculator:

  1. Enter Common Homozygotes: Input the number of individuals with the most common genotype.
  2. Enter Heterozygotes: Input the number of individuals with mixed genotypes.
  3. Enter Rare Homozygotes: Input the number of individuals with the least common genotype.

Example Inputs

  • Common Homozygotes: 100
  • Heterozygotes: 50
  • Rare Homozygotes: 30

Formula

The formula used for Hardy-Weinberg equilibrium is:

p2+2pq+q2=1

Variables

Symbol Explanation
p2 Frequency of common homozygous individuals
2pq Frequency of heterozygous individuals
q2 Frequency of rare homozygous individuals

How to Calculate Hardy-Weinberg Equilibrium

Follow these steps to calculate:

Step 1: Calculate the total population.

Total = Common Homozygotes + Heterozygotes + Rare Homozygotes

Step 2: Calculate the frequency of allele p.

p=2×Common Homozygotes+Heterozygotes2×Total

Step 3: Calculate the frequency of allele q.

q=1p

Step 4: Calculate expected frequencies:

Expected Common Homozygotes = Total×p2

Expected Heterozygotes = Total×2pq

Expected Rare Homozygotes = Total×q2

Example Solved

Step 1:

Total = 100 + 50 + 30 = 180

Step 2:

p=2×100+502×180=0.694

Step 3:

q=10.694=0.306

Step 4:

Expected Common Homozygotes = 180×(0.694)2

Expected Heterozygotes = 180×2×0.694×0.306

Expected Rare Homozygotes = 180×(0.306)2

Calculation Example

Basic Example Advanced Example
Common Homozygotes: 90 Common Homozygotes: 200
Heterozygotes: 60 Heterozygotes: 100
Rare Homozygotes: 50 Rare Homozygotes: 50
Total: 200 Total: 350
p: 0.675 p: 0.786
q: 0.325 q: 0.214
Expected Common Homozygotes: 91.13 Expected Common Homozygotes: 216.85
Expected Heterozygotes: 87.75 Expected Heterozygotes: 117.57
Expected Rare Homozygotes: 21.12 Expected Rare Homozygotes: 15.58

FAQs

What is Hardy-Weinberg equilibrium used for?

It helps in studying genetic variation and understanding evolutionary processes.

Can I use this calculator for any species?

Yes, as long as you have the necessary genotype frequencies.

Why is my calculation not matching?

Ensure all inputs are correct and check for any calculation errors.

Conclude

How did the Hardy-Weinberg Equilibrium Calculator work for you? We hope it provided valuable insights into genetic equilibrium. Share your experience and feedback; we’d love to hear how the tool helped you!

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